ISACP Webinars

October 3, 2023 - Biomarkers of Inherited Diseases in Animals: Several inherited diseases affect domestic animal species and present diagnostic challenges. This webinar will cover a wide range of inherited diseases, primarily in dogs, cats, and cattle, and the biomarkers available for making a clinical (laboratory) diagnosis. Biomarkers that will be discussed include leukocyte inclusions, magnetic resonance imaging, and urine derivatives analyzed by GC-MS. Inherited diseases will include lysosomal storage diseases such as gangliosidosis, mucopolysaccharidosis, and neuronal ceroid-lipofuscinosis; erythrocyte enzymopathies such as pyruvate kinase deficiency; immune disorders such as trapped neutrophil syndrome; coagulopathies such as hemophilia; and other inborn errors of metabolism. Presented by Dr. Osamu Yamato, DVM, PhD

Webinar Series on Iron Metabolism presented by John W. Harvey, DVM, PhD, DAVCP.

July 19, 2022 - Physiology of Iron Metabolism: This webinar topics include iron functions, iron absorption, and intracellular and systemic regulation of iron metabolism; transferrin, non-transferrin-bound iron and plasma iron utilization; roles of haptoglobin and hemopexin in iron metabolism and iron release from senescent erythrocytes; iron stores and serum ferritin; macrophage iron metabolism and ferritinophagy; liver iron metabolism and metabolic pathways controlling hepcidin production; and erythrocyte iron metabolism, including heme control of hemoglobin synthesis and erythropoiesis and feedback inhibition of hepcidin synthesis.

July 21, 2022 - Disorders of Iron Metabolism: This webinar’s topics include alterations in serum/plasma iron and ferritin concentrations in disease; the pathophysiology of hepcidin in iron deficiency, increased erythropoiesis, iron overload, and inflammation; hypoxia and iron metabolism, hematologic findings during iron deficiency in neonate and adult animals of various species, response to iron therapy, and possible mechanism of thrombocytosis that is frequently present; iron-refractory iron-deficiency anemia; pathophysiology of the anemia of inflammatory disease with focus on iron metabolism; iron-limited versus iron-deficient erythrocyte metabolism; portosystemic shunts; reticulocyte indices and iron metabolism; free heme toxicity and erythroid aplasia in cat with FeLV-C; excess iron associated with hemolytic anemia, dyserythropoiesis, and acute iron toxicity; hemosiderosis and hemochromatosis associated with PK-deficient dogs, repeated blood transfusions, dietary iron overload, and hereditary hemochromatosis; and disorders with and siderocytes and sideroleukocytes in blood.

Webinar Series on Acute Phase Reactants in Zoo and Wildlife Species

April 18, 2023 - Lecture 1: Introduction to APP and Applications in Zoo and Wildlife Species: This webinar will serve as a primer to acute phase proteins (who, what, where, why) and the demonstrated utility in companion and large animals.  Applications in zoo and wildlife species – both specific and overarching will also be presented. Presented by Professor Carolyn Cray, Ph.D.

February 7, 2023 - The Role of Haemostasis in the Pathogenesis of Disease: This webinar examines the mechanisms and implications of aberrant haemostasis in inflammation and cancer. Topics include: coagulation activation during the acute inflammatory response; the role of platelets in linking haemostasis, inflammation, and tissue injury; platelets as mediators of cellular communication; tumor expression of tissue factor; and mechanisms of coagulation-dependent metastasis. Disease examples will include acute babesiosis in dogs, canine parvovirus enteritis, African horse sickness, as well as carcinoma and sarcoma in dogs. Presented by Professor Amelia Goddard, BVSc(Hons), MMedVet, PhD